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Faculty of art and science department of molecular biology and genetics undergraduate program




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HITIT UNIVERSITY

FACULTY OF ART AND SCIENCE

DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS UNDERGRADUATE PROGRAM
I. SEMESTER/FIRST YEAR

General Biology-I (4 0 4)

Scientific method, the formation of organisms, evolution, biological molecular cell structure, cell theory, cell division, gametogenesis, egg types, fertilization and segmentation, protein synthesis, reproductive types, photosynthesis, chemosynthesis and events in the cellular respiratory.



Textbook

  • Genel Biyoloji 1. Cilt, William T. Keeton James L. Gould 5. Baskı, 2007, Ankara, Palme Yayınevi

General Biology-I Laboratory (0 2) 1

The subjects are including following; The properties and the use of light microscopy, The properties and the use of a dissecting microscope, The characteristics of the electron microscope, Robert Hooke's cell, Cell structure in plants and animals, Plastids in plants (chloroplasts, chromoplasts and leucoplasts), Plasmolysis and deplasmolysis in plants, Cell division (mitosis), The structure of a bacteria, Animal tissue (blood cells), Proliferation of yeast by budding, Cytoplasmic inclusion bodies in plant cells, Pigment granules in animal cells (fish scales in pigment cells), Rotation and circulation in cells, Crystals in plants (druz, sistolit ve rafid).



Textbook

  • Arslan, O., Bahar M., Özel A., Genel Biyoloji Lab. Klavuzu, Palme Yayıncılık

General Chemistry-I (3 0) 3

Introduction: (the matter, the metric system, significant figures), atomic structure, the periodic table, chemical bonds; molecular geometry, chemical equations and quantitative relations, oxidation and reduction reactions, gas, liquid, solutions.



Textbook

• Genel Kimya, Temel Kavramlar, Raymond Chang, Mart 2007 / 4. Baskı / 752 Syf.



General Mathematics-I (4 0 4)

Sets and numbers, absolute value and intervals, lines, functions and limits, continuity, derivatives, applications of differential, the mean value theorem, integrals, mean value theorem for integrals. Inverse functions, logarithms and exponential functions, integration methods, applications of integral, sequences and series, polar coordinates, multiple integrals, elementary differential equations.



Textbooks

  • Genel Matematik – 1, Osman Bizim, Ahmet Tekcan, Betül Gezer, Ocak 2012 / 3. Baskı / 344 Syf.

  • Genel Matematik – 2, Osman Bizim, Ahmet Tekcan, Betül Gezer, Ocak 2012 / 2. Baskı / 643 Syf.

Suplementary

  • Sağlık Bilimciler ve Biyologlar için Matematik. R. Kaya, Anadolu Üniversitesi, 234 s.

General Physics -I (4 0) 4

Physics and measurement, vectors, motion in one dimension, , motion in two dimension, laws of motion, circular motion, work and energy, conservation of energy, linear momentum and collisions, around the axis of rotation of a rigid body, universal law of attraction, fluid mechanics.

Electric fields, Gauss' law, electric potential, capacitance and dielectrics, current and resistance, DC circuits, magnetic fields, magnetic field sources, Faraday's law, inductance, alternating current circuits, electromagnetic waves.

Textbook


  • Halliday, D. & Resnick, R. (2002). Çeviri Editörü: Yalçın, C. Fiziğin Temelleri. Ankara: Arkadaş Yayınevi

Suplementary

  • Serway, R.A. (1990). Çeviri Editörü: Çolakoğlu, K. Fen ve Mühendislik için Fizik. Ankara: Palme Yayıncılık.

  • Ohanian, H.C. (1989). Physics. New York: W.W. Norton & Compony, Inc.

  • Fishbane, P.M., Gasiorowicz, S., & Thornton, S.T. (2003). Çeviri Editörü: Türkoğulları, Ü. Temel Fizik. Ankara: Arkadaş Yayınevi.


Turkish Language I (2-0) 2

It is aimed to develop the correct use and writing skills of the Turkish in the lecture including grammar rules and spelling rules.



Textbook

  • Türk Dili ve Kompozisyon Bilgileri, (Heyet), Yargı Yayınevi, Ankara 2003.

Suplementary Textbooks

  • Türkçe Dilbilgisi, Kaya Bilgegil, Dergâh Yayınları, İstanbul, 1984.

  • Yazım Kılavuzu, Türk Dil Kurumu Yayınları, Ankara, 2005.

  • Her Yönüyle Dil, Doğan Aksan, Türk Dil Kurumu Yayınları, Ankara, 2003.

History of Ataturk's Principles Revolutions I (2 0) 2

Political, economic, cultural and socio-psychological problems resulting from the encountering of Western cultures with Turkish culture, at the collapsing of Ottoman state, the reform movements in the framework of the search for solutions in the Ottoman state, Political events in the process of transition from empire to national state, the founding of the Republic of Turkey as a result of the National Struggle given by the leading of Mustafa Kemal Atatürk, revolution period after the Lausanne Peace Conference, multi-party democracy transition trials and politics in II. World War and political events.



Textbooks

  • Komisyon, Atatürk İlkeleri ve Devrim Tarihi II, Uludağ Üniversitesi Yayınları, Bursa 2008.

  • Atatürk'ün Söylev ve Demeçleri, I-III, Atatürk Araştırma Merkezi, Ankara, 1997.

Ecology (2 0) 2

The definition of Ecology and environmental sciences, the historical change of Earth and its effects on formation of species, some of basic concepts and theories in Ecology, Abiotic factors and effects on organisms, Biotic factors, population and its structural characteristics, population dynamics, community and its properties, Ecosystems and its properties major ecosystems of the World, Ecological problems of humanity, Conservation of the Nature, Environmental protection and new approaches on Regulation.



Textbook

  • Y. Şahin, Ekoloji, Bilim Teknik Yayınevi.

Foreign Language-I (2-0) 2

In this lecture, basic English grammar features will be taught. At the end of the semester, students should have learned basic grammatical features of the English language and aim to develop them by writing, listening, reading and speaking.


Textbook


II. SEMESTER/ FIRST YEAR

General Biology-II (4 0) 4

Fundamentals of animal classification, animal tissues, animal systems, Fundamentals of animal ecology, plant tissue and characteristics, organographies (vegetative organs), seeds and seed plant general properties of seed and seedless plants, the basic concepts of plant physiology.



Textbook

  • Genel Biyoloji 1. Cilt, William T. Keeton James L. Gould 5. Baskı, 2007, Ankara, Palme Yayınevi

Suplementary

  • Genel Biyoloji, Abdurrahman Aktümsek, Muhsin Konuk. 3. Baskı, 2010, Nobel Yayın Dağıtım.

General Biology-II Laboratory (0 2) 1

Preparation and examination of protozoa culture, animal tissue examination, examining animals belonging to different taxa, examination of plant tissues belonging to different plant groups, examination anatomical and morphological structure of root, stem, leaf and fruit, examination of plant samples of seed and seedless plants.



Textbook

  • Arslan, O., Bahar M., Özel A., Genel Biyoloji Lab. Klavuzu, Palme Yayıncılık

General Chemistry-II (3 0) 3

Electrochemistry, chemical kinetics and chemical equilibrium, chemical thermodynamics, acids and bases, ionic equilibrium, introduction to organic chemistry.



Textbook

  • Genel Kimya, Temel Kavramlar, Raymond Chang, Mart 2007 / 4. Baskı / 752 Syf.

Suplementary

  • Maddeler ve Değişimler, Temel Kimya – 2 Moleküller, Peter Atkins, Loretta Jones, Ocak 1999 / 1. Baskı / 449 Syf.



General Chemistry Laboratory -II (0 2) 1

Introduction of laboratory glassware, the chemical properties of matter, chemical reaction types, chemical equilibrium, stoichiometry, diffusion, determination of molar mass with freezing point depression, determination of a magnesium equivalent grams of mass, buffer solutions, indicators and pKa determination, acid-base titration, ideal gas constant calculation, the effect of temperature on reaction rate tests.



Textbook

  • Genel Kimya Laboratuvarı 1-2, Hikmet Sayılkan Hüseyin Bağ Funda Sayılkan Bilge Emre, Pagem Akademik Yayıncılık

Introduction to Computer Usage (1 2) 2

Introduction to Computers, basic concepts, Working principle of computers, Binary number system, Bit-byte concept, Computer hardware, components roles, definitions, Software types, operating systems, application software, programming languages, Introduction to Dos-windows operating system. File, directory, drive definitions, windows explorer usage, desktop settings. Start menu commands, control tools, display of system tools programs. Antivirus programs, compression programs, demonstration of the use of image processing programs. Introduction to office programs, explaining the interface, menus, toolbars and views of the word processing program. Different Word applications, Introduction to spreadsheet program, cell structure, page structure, display of data transfer between cells, numerical calculations. Different Excel applications.



Textbook

  • Tüm Müfredat Bilgisayar Teknolojisi ve Kullanımı, Sedat Temur ve K. Yalçın, Çizgi Yayın, Konya, 2001

Biophysics (3 0) 3

Interpretation of biological phenomena in terms of physical concepts such as structure, information and energetics, Atom and molecular structure and information about chemical bonds, Structural and functional properties of biomolecules and cell building blocks, Bioenergetics and information theory which are closely related to bioenergetics, Cybernetics and kinetics (enzyme) science, The Progression from single cell to multi cell, Embryonic development, Cell proliferation and differentiation, Regulation and control mechanism of them (cancer that develops with the removing of control)



Textbook

  • Ders notları

Turkish Language II (2-0) 2

Sentence Information, Types of Written and Oral Composition, Characteristics of Prepared and Unprepared Speech (Examples of Conference Presentations in Different Topics), Types of Written Expression (thesis, report, minutes etc.) and Sample Texts. Different Texts from Turkish and World Literature



Textbook

  • TDK Dilbilgisi; AK, Coşkun.


History of Ataturk's Principles Revolutions II (2 0) 2

In the context of Atatürk's Principles and Revolutions, which is organized in parallel with the establishment of the Republic of Turkey, the Turkish and the restructuring of the state and the society, the internal and external political events that are faced with political, social, economic and cultural developments and changes that are taking place in our society, is evaluated.



Textbook

  • Komisyon, Atatürk İlkeleri ve Devrim Tarihi II, Uludağ Üniversitesi Yayınları, Bursa 2008.

  • Atatürk'ün Söylev ve Demeçleri, I-III, Atatürk Araştırma Merkezi, Ankara, 1997.

Suplementary

  • Bernard Lewis, Modern Türkiye’nin Doğuşu, Türk Tarih Kurumu Yay., Ankara 1993.

  • İsmet Görgülü, Ana Hatlarıyla Türk İstiklal Harbi, Kastaş Yayınları, İstanbul 1985.

  • Mustafa Kemal Atatürk, Söylev, I-II, (Haz. H.V. Velidedeoğlu), Çağdaş Yay., İstanbul 1988.

Foreign Language-II (2-0) 2

Speaking, Writing, Reading and Listening experiences will be tried to develop in this lecture. In addition, students will also need to be able to read and understand works such as books and articles that will be welcomed in their next academic life and to be able to express in Turkish. For this reason, translation techniques will also be emphasized. At the end of the semester, students should have learned basic grammatical features of the English language and aim to develop them by writing, listening, reading and speaking.



Textbook

  • Advanced Grammer in Use, Martin Hewings, Cambridge University Press, 2003.


ÜÇÜNCÜ DÖNEM/ İKİNCİ YIL

Cytology (3 0) 3

History of Cell Biology, cell structure, tools of biological structure investigations, chemical and other techniques used in examinations of cells, chemical structure of cell and biosynthesis, bioenergetics, the structure and properties of cell membrane, cell membrane's variations, endocytosis and exocytosis, Transport thermodynamics of energy transformations in mitochondria and chloroplasts, organelle structure and functions (nucleus, mitochondria, endoplasmic reticulum, ribosomes, golgi complex, lysosomes, peroxisome and vacuole), Intracellular trafficking of proteins, Membrane fusion and vesicular transport, Cytoskeleton.



Textbook

  • S. Karol, C. Ayvalı, Z. Suludere, Hücre Biyolojisi, Azim Maatbcılık.

Suplementary

  • G. M. Cooper, Hücre: Moleküler Yaklaşım

  • H. V. Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi.

Cytology Lab I (0 2) 1

Equipment for examination of biological structures, investigation of the cells, light microscope, polarizing microscope, interference microscope, phase-contrast microscope, X-ray diffraction, structure of eukaryotic cell, structure of animal cell, structure of plant cell, structure of prokaryotic cell, structure of plasma membrane, differentiations on the plasma membrane, endocytosis and exocytosis, structure of microtubules, structure of microfilaments, structure of endoplasmic reticulum, structure of mitocondria, structure of golgi apparatus, structure of lysosome, structure of centriols, structure of ribosomes, structure of nucleus, structure of nucleolus, structure of chromatine, structure of chromosome, chemical and other techniques used in the examination of cells.



Textbook

  • M. Ünal, F. Vardar, I. İsmailoğlu, Hücre Biyolojisi Lab., Nobel Yayın Dağıtım.

Organic Chemistry (3 0) 3

Carbon compounds and chemical bonds, sigma and pi bonds. Alkanes and cycloalkanes, be designated, and the free radical reactions. The structures, synthesis alkenes, and addition reactions of alkenes. Stereochemistry. Alkyl halides, nucleophilic substitution and elimination reactions. Alkynes, structures, synthesis and reactions. Conjugated unsaturated systems and addition reactions. The concept of aromatic compounds and aromatic. Electrophilic aromatic substitution reactions. Alcohols, phenols and ethers, be designated the synthesis and reactions. Aldehydes and ketones, nucleophilic addition reactions to the carbonyl group and on the a-carbon reactions. Carboxylic acids and derivatives thereof, their synthesis and the acyl carbon of the nucleophilic displacement reactions. Amines, nomenclature, preparation and reactions.



Textbook

  • Organic Chemistry with Biological Applications, 2nd Ed., John McMurry, 2007

Suplementary

  • Organik Kimya Tıp ve Biyoloji Öğrencileri İçin, Prof. Dr. Mustafa AKPOYRAZ, Güneş Tıp Kitabevi

  • Organic Chemistry, Mc Murry, 2008



Molecular Biology I ( 3 0) 3

The structures and properties of biological macromolecules, Nucleotides building blocks of DNA, Structure and function of DNA and RNA, Genome structure, Organization of chromosomes, Duplication and seperation of chromosomes, Transcription and post-transcriptional modifications, Structure and functions of proteins, DNA replication in prokaryotes and eukaryotes, DNA repair mechanisms.



Textbook

  • Moleküler Biyoloji, N. DİLSİZ, Palme Yayıncılık, 2009.

Suplementary

  • G. M. Cooper, Hücre: Moleküler Yaklaşım

Molecular Biology Lab I ( 0 2) 1

Working principles of molecular biology laboratory instruments and apparatus, DNA isolation and quantitative analysis, Polymerase Chain Reaction (PCR) and optimization techniques, Gel electropheresis and analysis, gel preparation techniques.



Textbook

  • N. Arda, G. Temizkan, Moleküler Biyolojide Kullanılan Teknikler, Nobel Yayın Dağıtım

Laboratory Technique and Job Safety (3 0) 3

General works health and safety rules, The reasons for occupational diseases and Risks in the laboratory. Ways of protection from accidents, injuries and diseases and protection techniques. Safe usage of lab. equipments, Informing about legal regulations. Risks arising from chemical, physical and biological agents, First aid and rescue.



Textbooks

  • Erdik, E., Obalı, M., Yüksekışık, N., Öktemer, A., Pekel, T. ve İhsanoğlu, E., "Denel Organik Kimya", (1997), A.Ü. Fen Fakültesi, Ankara;

  • Soydan A. B., Koza G., Tan N., Tunca Ü. Genel Kimya Laboratuar Kitabı.

Biostatistics (3 0) 3

Descriptive statistics, possibility, frequency distributions, guessing, t and x2 tests, sampling. Korelasyon, Recreation, Variance Analysis, Nonparametric Methods, Demography, Index Numbers, Numerical Taxonomy.



Textbook

  • Çömlekçi, N., (2005), Temel İstatistik İlke ve Teknikleri, Bilim Teknik Yayınevi, Eskişehir.

Suplementary

  • Özdamar, K., (1999), SPSS ile Biyoistatistik, Kaan Kitabevi, Eskişehir.

  • Sümbüloğlu, K., Sümbüloğlu, V., (1990), Biyoistatistik , Hatipoğlu Kitabevi, Ankara


FOURTH PERIOD / SECOND YEAR

Tissue Biology (3 0) 3

Epithelial tissue, General features of epithelial tissue, Classification of epithelium and Epithelial Cell Types, Connective Tissue, Ground substance, Cells and wires, Connective Tissue Types, Adipose Tissue, Unilocular and Multilocular Adipose Tissue, Blood, Blood cells, blood platelets and Hematopoiesis, Cartilage tissue, Hyaline, Elastic and Wire (Fibrous) Cartilage, Bone tissue, Bone Cells, Matrix, Periosteum and Endosteum Bone Cell Types, Nerve Tissue, Neurons, Synapses, Neuroglia



Textbook

  • Genel Histoloji, Prof.Dr. Turan AKAY(2006)

Suplementary

  • Temel Histoloji, Prof.Dr. Yener AYTEKİN (1998)

  • Histoloji, Prof.Dr. Şermin PAKER (1993)

  • Genel Histoloji Atlası, Prof.Dr. Turan AKAY(2004)


Tissue Biology Laboratory (0 2) 1

Theoretically, taking, painting and microscopically examining all the sections of the described tissues.



Textbook

Ders notları



Plant Anatomy and Physiology (4 0) 4

The subject, scope and history of plant anatomy and physiology, The links between plant functions and the functions of plant anatomy and morphology, Internal structure and functions of plant cells, Structure of tissues and structure of organs, Anatomical features of plant cells and tissues, Chemical Composition of Plant Cells, Cell Wall and Membrane Systems, Permeability, Water and plant Cells, Contents and Functions of Water which in Plant Cells, Basic Events in Plant-Water Relationships, Water Use in Plant cells, Basic Events Related to Acquisition, Transport and Translocation of Water and Melt in Plant Cells, Transport Processes, Biophysics and Biochemistry of Photosynthesis, Light Reactions of Photosynthesis, Physiological and Ecological Importance of Carbon Metabolism, Movement physiology, stress physiology.



Textbook

  • Plant Anatomy and Physiology. Aslam Kham. Kalpaz Publition in India, 2001

Suplementary

  • Plant Physiology, Taiz, L., Zeiger, E.,

  • Bitki Fizyolojisi, Ömer Bozdoğan

  • Bitki Fizyolojisi, Önder, N., Yentür, S.,

  • Yentür, S. (2000). Bitki Anatomisi. İstanbul Üniversitesi, Fen Fakültesi Yayınları, İstanbul.

  • Bitki Fizyolojisi, Kadıoğlu, A.,

  • Fotosentez, Akman, Y., Küçüködük, M., Evren, H., Öncel, I., Düzenli

  • Esau, K. (1977). Anatomy of Seed Plants. University of California, Santa Barbara, California.

Molecular Biology II ( 3 0) 3

DNA replication, Mutations and DNA repair, homolog recombination, transposition, Cell connections, Cell adhesion and Extracellular matrix, gametes and fertilization, Cellular mechanisms of development, Maintenance and repair of differentiated cells and tissues, cancer, The foundations of genetic engineering, Molecular biology of the immune system



Textbook

  • Moleküler Biyoloji, N. DİLSİZ, Palme Yayıncılık, 2009.

  • Genetik, A. N. Bozcuk, Palme Yayıncılık.

Suplementary

  • G. M. Cooper, Hücre: Moleküler Yaklaşım

Molecular Biology Laboratory II ( 0 2) 1

Isolation of genomic DNA from human blood cells, DNA isolation from human cheek epithelial cells, PCR and applications, Methods used to identify the DNA mutations.



Textbook

  • N. Arda, G. Temizkan, Moleküler Biyolojide Kullanılan Teknikler, Nobel Yayın Dağıtım

Biodiversity (3 0) 3

Genetic diversity, Species diversity, Ecosystem diversity, Ecological diversity, Advantages on ecosystem functions, Economic benefits and prosperity of biodiversity, Benefits as nutrient and gene source, importance of Biodiversity, Ecology of biodiversity, Environmental health and tourism importance, importance of biodiversity in terms of culture and art, causes of biodiversity in Turkey, diversity of flora and fauna of Turkey.



Textbook

  • Anonim. Türkiye’ nin Biyolojik Zenginlikleri, Türkiye Çevre Vakfı Yayını, 2005.





Immunology (2 1) 3

Primary and secondary lymphoid organs and tissues, Lymphoid cells, Mononuclear phagocytes, polymorphonuclear cells, Mast cells and platelets, complement, inflammation, antibodies, T cell receptors and MHC molecules, Antibody and T cell diversity, Antigen recognition and presentation, Cellular immunological response, Intercellular communication in antibody response, Cytokines, Regulation of immunological responses, Immunological tolerance, Immune response to the virus, Immunological response to bacteria and fungi, Parasite immunology, tumor immunology, primer immunodeficiency, secondary immunodeficiency, type I hypersensitivity reactions, Type II and type III hypersensitivity reactions, type IV hypersensitivity reactions, transplantation and rejection immunology, autoimmunity, immunological diagnostic methods.



Textbook

  • Temel ve Klinik Mikrobiyoloji, Şemsettin Ustaçelebi, 1.Baskı, Güneş Kitabevi, Ankara, 1999.

Suplementary

  • Immunobiology, Janeway, Travers, Walport, Shlomchik, 6th Ed., Garland Science Publishing, USA, 2005.

FIFTH PERIOD / THIRD YEAR

Biochemistry I (3 0) 3

Different systems such as Cell, Amino Acids, Peptides, Proteins, Enzymes, Nucleic Acids, Carbohydrates, Lipids and Membranes, Oils, Vitamins, Hormones and Immune System are examined.


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Faculty of art and science department of molecular biology and genetics undergraduate program

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